ENIGMA: Ecosystems and Networks Integrated with Genes and Molecular Assemblies
IMPACT: Integrated Metallo-Protein Analytical Comparison Tool

This web site contains research data from the U. S. Department of Energy's ENIGMA project. This data is described in the publication: "A Computational Framework for Proteome-Wide Pursuit and Prediction of Metalloproteins using ICP-MS and MS/MS Data". Detailed data for each protein discussed in this publication can be viewed by clicking on the corresponding link below. A separate chart is displayed for each column in which the protein was detected. The number of peptides detected for each fraction within the column are indicated by yellow bars. Peptide counts are displyed even if only a single peptide was detected, however only fractions with two or more detected peptides contribute to the GMPA score. Metal concentration plots for any of the ten metals detected can be viewed by clicking the links at the top of each protein detail page. Backgound information on the computational and experimental methods used to generate and analyze the data can be found in the following publications:

A Computational Framework for Proteome-Wide Pursuit and Prediction of Metalloproteins using ICP-MS and MS/MS Data
Lancaster WA, Praissman JL, Poole FL II, Cvetkovic A, Menon AL, Scott JW, Jenney FE Jr., Thorgersen MP, Kalisiak E, Apon JV, Trauger SA, Siuzdak G, Tainer TA and Adams MWW. BMC Bioinformatics (submitted)

Microbial metalloproteomes are largely uncharacterized
Cvetkovic A, Menon AL, Thorgersen MP, Scott JW, Poole FL II, Jenney FE Jr, Lancaster WA, Praissman JL, Shanmukh S, Vaccaro BJ, Trauger SA, Kalisiak E, Apon JV, Siuzdak G, Yannone SM, Tainer JA, Adams MWW.
Nature. 2010 Aug 5;466(7307):779-82.

Novel multiprotein complexes identified in the hyperthermophilic archaeon Pyrococcus furiosus by non-denaturing fractionation of the native proteome
Menon AL, Poole FL II, Cvetkovic A, Trauger SA, Kalisiak E, Scott JW, Shanmukh S, Praissman JL, Jenney FE Jr, Wikoff WR, Apon JV, Siuzdak G, Adams MWW. Mol Cell Proteomics. 2009 Apr;8(4):735-51.

This work conducted by ENIGMA was supported by the Office of Science, Office of Biological and Environmental Research, of the U. S. Department of Energy under Contract No. DE-AC02-05CH11231.


 ORFIPM Hits
SelectPF00084
SelectPF0009 
SelectPF0010 
SelectPF0014 
SelectPF0015 
SelectPF0016 
SelectPF0018 
SelectPF0019 
SelectPF00206
SelectPF0022 
SelectPF00261
SelectPF0027 
SelectPF00371
SelectPF00386
SelectPF0039 
SelectPF00411
SelectPF0042 
SelectPF0043 
SelectPF0048 
SelectPF0049 
SelectPF0050 
SelectPF0053 
SelectPF00563
SelectPF0059 
SelectPF0060 
SelectPF00687
SelectPF0070 
SelectPF00711
SelectPF00754
SelectPF0078 
SelectPF0079 
SelectPF0086 
SelectPF0087 
SelectPF0092 
SelectPF0093 
SelectPF00942
SelectPF009528
SelectPF009632
SelectPF0097 
SelectPF0098 
SelectPF0099 
SelectPF0100 
SelectPF0102 
SelectPF010721
SelectPF0108 
SelectPF0111 
SelectPF0112 
SelectPF011314
SelectPF0121 
SelectPF0122 
SelectPF0124 
SelectPF0125 
SelectPF0126 
SelectPF0127 
SelectPF0128 
SelectPF0133 
SelectPF0135 
SelectPF0136 
SelectPF013810
SelectPF01392
SelectPF0142 
SelectPF01441
SelectPF0145 
SelectPF01466
SelectPF01476
SelectPF0149 
SelectPF0151 
SelectPF0153 
SelectPF0154 
SelectPF0155 
SelectPF0157 
SelectPF0159 
SelectPF0160 
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SelectPF0162 
SelectPF0164 
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SelectPF0166 
SelectPF01726
SelectPF017515
SelectPF0176 
SelectPF0177 
SelectPF0181 
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SelectPF0184 
SelectPF0185 
SelectPF018711
SelectPF01896
SelectPF01946
SelectPF01963
SelectPF0199 
SelectPF0200 
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SelectPF02021
SelectPF0203 
SelectPF0207 
SelectPF0209 
SelectPF02101
SelectPF02128
SelectPF0215 
SelectPF02185
SelectPF0220 
SelectPF0221 
SelectPF0222.1 
SelectPF0223 
SelectPF0225 
SelectPF023028
SelectPF0231 
SelectPF023228
SelectPF0233 
SelectPF02351
SelectPF02362
SelectPF0241 
SelectPF0246 
SelectPF02478
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SelectPF0249 
SelectPF0250 
SelectPF0252 
SelectPF0253 
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SelectPF0256 
SelectPF02572
SelectPF02586
SelectPF0264 
SelectPF0265 
SelectPF0268 
SelectPF0270 
SelectPF02722
SelectPF0276 
SelectPF0282 
SelectPF0284 
SelectPF0285 
SelectPF028910
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SelectPF0298 
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SelectPF0306 
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SelectPF03103
SelectPF0312 
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SelectPF03181
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SelectPF0339 
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SelectPF034457
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SelectPF0351 
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SelectPF03544
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SelectPF0355.1 
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SelectPF03693
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SelectPF04566
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SelectPF0469 
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SelectPF04826
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SelectPF0512 
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SelectPF05262
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SelectPF053335
SelectPF05344
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SelectPF05479
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SelectPF0565 
SelectPF0566 
SelectPF0569 
SelectPF0572 
SelectPF058812
SelectPF05893
SelectPF0590 
SelectPF0591 
SelectPF05937
SelectPF0594 
SelectPF0595 
SelectPF05978
SelectPF0598 
SelectPF0599 
SelectPF0601 
SelectPF0604 
SelectPF060735
SelectPF06084
SelectPF06125
SelectPF0613 
SelectPF06153
SelectPF0616 
SelectPF061712
SelectPF0619 
SelectPF0620 
SelectPF0624 
SelectPF0637 
SelectPF0639 
SelectPF0640 
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SelectPF0642 
SelectPF0643 
SelectPF064914
SelectPF0652 
SelectPF0657 
SelectPF0667 
SelectPF0668 
SelectPF0669 
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SelectPF0676 
SelectPF0677 
SelectPF0678 
SelectPF0680 
SelectPF0691 
SelectPF06929
SelectPF0693 
SelectPF069410
SelectPF06958
SelectPF06963
SelectPF0703 
SelectPF0704 
SelectPF0706 
SelectPF0715 
SelectPF0716 
SelectPF07173
SelectPF0721 
SelectPF07222
SelectPF0725 
SelectPF0726 
SelectPF072720
SelectPF073914
SelectPF074223
SelectPF0747 
SelectPF0750 
SelectPF07518
SelectPF07522
SelectPF07531
SelectPF07548
SelectPF0755 
SelectPF0765 
SelectPF0767 
SelectPF07681
SelectPF0770 
SelectPF0771 
SelectPF0776.1 
SelectPF0792 
SelectPF0794 
SelectPF0804 
SelectPF0812 
SelectPF0813 
SelectPF0816 
SelectPF0818 
SelectPF0820 
SelectPF0825 
SelectPF0828 
SelectPF082935
SelectPF0838 
SelectPF0839 
SelectPF084535
SelectPF08461
SelectPF08507
SelectPF08511
SelectPF0853 
SelectPF08562
SelectPF086112
SelectPF0862 
SelectPF0863 
SelectPF086414
SelectPF0865 
SelectPF08681
SelectPF0869 
SelectPF0872 
SelectPF0873 
SelectPF08742
SelectPF0875 
SelectPF088014
SelectPF0890 
SelectPF089131
SelectPF089211
SelectPF08936
SelectPF089412
SelectPF08953
SelectPF0897 
SelectPF0902 
SelectPF0903 
SelectPF09053
SelectPF0908 
SelectPF0929 
SelectPF0931 
SelectPF0937 
SelectPF093931
SelectPF09403
SelectPF09422
SelectPF0959 
SelectPF0963 
SelectPF09651
SelectPF09666
SelectPF096734
SelectPF09681
SelectPF09696
SelectPF097034
SelectPF09714
SelectPF0972 
SelectPF0973 
SelectPF0974 
SelectPF09759
SelectPF0980 
SelectPF0983 
SelectPF0985 
SelectPF098621
SelectPF0988 
SelectPF0989 
SelectPF0990 
SelectPF099160
SelectPF0994 
SelectPF0996 
SelectPF0997 
SelectPF1002 
SelectPF1016 
SelectPF1017 
SelectPF10221
SelectPF1024 
SelectPF1025 
SelectPF1026 
SelectPF10301
SelectPF1031 
SelectPF10332
SelectPF10342
SelectPF1035 
SelectPF1036 
SelectPF1039 
SelectPF10428
SelectPF1043 
SelectPF104520
SelectPF10462
SelectPF1051 
SelectPF1055 
SelectPF1056 
SelectPF10593
SelectPF106052
SelectPF10612
SelectPF1063 
SelectPF1065 
SelectPF1066 
SelectPF1076 
SelectPF10832
SelectPF1085 
SelectPF1096 
SelectPF1097 
SelectPF1099 
SelectPF11016
SelectPF1102 
SelectPF1104 
SelectPF1105 
SelectPF11074
SelectPF110917
SelectPF1111 
SelectPF1113 
SelectPF1114 
SelectPF1115 
SelectPF1116 
SelectPF1117 
SelectPF1121 
SelectPF1122 
SelectPF1123 
SelectPF1124 
SelectPF1125 
SelectPF1126 
SelectPF1128 
SelectPF1129 
SelectPF1132 
SelectPF1134 
SelectPF11365
SelectPF1137 
SelectPF1138 
SelectPF1140 
SelectPF1141 
SelectPF1142 
SelectPF1143 
SelectPF1146 
SelectPF1155 
SelectPF11565
SelectPF1165 
SelectPF116720
SelectPF1169 
SelectPF1176 
SelectPF118511
SelectPF11864
SelectPF119010
SelectPF1191 
SelectPF119210
SelectPF119319
SelectPF119510
SelectPF119610
SelectPF11972
SelectPF1198 
SelectPF119910
SelectPF1201 
SelectPF120328
SelectPF1204 
SelectPF1205 
SelectPF12136
SelectPF1214 
SelectPF1222 
SelectPF1236 
SelectPF12383
SelectPF1241 
SelectPF124227
SelectPF1243 
SelectPF124510
SelectPF1246 
SelectPF1253 
SelectPF1258 
SelectPF1262 
SelectPF1264 
SelectPF1266 
SelectPF1267 
SelectPF1269 
SelectPF1270 
SelectPF1272 
SelectPF1275 
SelectPF12773
SelectPF12785
SelectPF128128
SelectPF12822
SelectPF128314
SelectPF1284 
SelectPF128544
SelectPF128644
SelectPF128717
SelectPF1288 
SelectPF1289 
SelectPF12911
SelectPF1293 
SelectPF1294 
SelectPF1295 
SelectPF12964
SelectPF1297 
SelectPF1299 
SelectPF13277
SelectPF132811
SelectPF132931
SelectPF133011
SelectPF133113
SelectPF133212
SelectPF1333 
SelectPF1334 
SelectPF133514
SelectPF13372
SelectPF13382
SelectPF1339 
SelectPF13404
SelectPF1341 
SelectPF1342 
SelectPF13434
SelectPF1344 
SelectPF1349 
SelectPF13516
SelectPF1355 
SelectPF1356 
SelectPF1357 
SelectPF1367 
SelectPF1368 
SelectPF1372 
SelectPF1374 
SelectPF1375 
SelectPF1376 
SelectPF137718
SelectPF1380 
SelectPF1381 
SelectPF1382 
SelectPF13834
SelectPF1385 
SelectPF1386 
SelectPF1387 
SelectPF1388 
SelectPF1390 
SelectPF1392 
SelectPF1393 
SelectPF1394 
SelectPF1395 
SelectPF1396 
SelectPF139711
SelectPF1398 
SelectPF1399 
SelectPF1401 
SelectPF14056
SelectPF14074
SelectPF14116
SelectPF14144
SelectPF1416 
SelectPF14181
SelectPF1419 
SelectPF1421 
SelectPF14222
SelectPF143240
SelectPF1433 
SelectPF143415
SelectPF1440 
SelectPF145451
SelectPF1458 
SelectPF1459 
SelectPF1461 
SelectPF1462 
SelectPF1471 
SelectPF1472 
SelectPF1475 
SelectPF1476 
SelectPF1477 
SelectPF147932
SelectPF148028
SelectPF1481 
SelectPF14822
SelectPF1483 
SelectPF1484 
SelectPF1486 
SelectPF1487 
SelectPF14891
SelectPF14906
SelectPF1491 
SelectPF1492 
SelectPF1497 
SelectPF1499 
SelectPF1500 
SelectPF1515 
SelectPF1516 
SelectPF1517 
SelectPF152133
SelectPF1528 
SelectPF1529 
SelectPF1530 
SelectPF15324
SelectPF1535 
SelectPF1538 
SelectPF1539 
SelectPF1540 
SelectPF1542 
SelectPF1543 
SelectPF15441
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SelectPF15472
SelectPF1548 
SelectPF1549 
SelectPF1556 
SelectPF1557 
SelectPF1558 
SelectPF1559 
SelectPF1560 
SelectPF1562 
SelectPF15632
SelectPF1564 
SelectPF1565 
SelectPF1568 
SelectPF1569 
SelectPF1570 
SelectPF1571 
SelectPF1572 
SelectPF1573 
SelectPF1574 
SelectPF1578 
SelectPF1579 
SelectPF1580 
SelectPF1582 
SelectPF1584 
SelectPF1587 
SelectPF1588 
SelectPF1589 
SelectPF1590 
SelectPF15913
SelectPF1593 
SelectPF15973
SelectPF159827
SelectPF16001
SelectPF1602 
SelectPF1603 
SelectPF1607 
SelectPF16112
SelectPF1615 
SelectPF1616 
SelectPF1619 
SelectPF1622 
SelectPF1623 
SelectPF1626 
SelectPF1627 
SelectPF16291
SelectPF1630 
SelectPF1631 
SelectPF1634 
SelectPF1635 
SelectPF1637 
SelectPF16385
SelectPF1640 
SelectPF1641 
SelectPF1642 
SelectPF16434
SelectPF1644 
SelectPF1646 
SelectPF1647 
SelectPF1648 
SelectPF1649 
SelectPF1650 
SelectPF1656 
SelectPF1657 
SelectPF1658 
SelectPF16591
SelectPF1660 
SelectPF1663 
SelectPF16642
SelectPF1666 
SelectPF1674 
SelectPF1675 
SelectPF167938
SelectPF168025
SelectPF1682 
SelectPF1683 
SelectPF1684 
SelectPF1685 
SelectPF168611
SelectPF1691 
SelectPF1693 
SelectPF1700 
SelectPF1702 
SelectPF1705 
SelectPF1706 
SelectPF1712 
SelectPF1714 
SelectPF1715 
SelectPF1717 
SelectPF17181
SelectPF1719 
SelectPF1720 
SelectPF1722 
SelectPF17231
SelectPF17281
SelectPF17293
SelectPF1731 
SelectPF173414
SelectPF1735 
SelectPF1738 
SelectPF17393
SelectPF1742 
SelectPF1743 
SelectPF174415
SelectPF1745 
SelectPF1746 
SelectPF1753 
SelectPF1758 
SelectPF1760 
SelectPF17646
SelectPF17661
SelectPF176732
SelectPF17686
SelectPF17704
SelectPF17716
SelectPF17722
SelectPF17732
SelectPF1778 
SelectPF178312
SelectPF1784 
SelectPF1787 
SelectPF1788 
SelectPF1789 
SelectPF179028
SelectPF1791 
SelectPF1792 
SelectPF1794 
SelectPF179539
SelectPF179632
SelectPF179710
SelectPF1798 
SelectPF1800 
SelectPF1803 
SelectPF1804 
SelectPF1805 
SelectPF1808 
SelectPF1809 
SelectPF1812 
SelectPF1814 
SelectPF1817 
SelectPF1818 
SelectPF1819 
SelectPF1821 
SelectPF1822 
SelectPF1824 
SelectPF1825 
SelectPF1827 
SelectPF1828 
SelectPF1829 
SelectPF1831 
SelectPF1832 
SelectPF1837 
SelectPF1838 
SelectPF1839 
SelectPF1842 
SelectPF18433
SelectPF1847 
SelectPF1848 
SelectPF18492
SelectPF1853 
SelectPF1858 
SelectPF1859 
SelectPF18612
SelectPF1862 
SelectPF1866 
SelectPF18674
SelectPF1869 
SelectPF1871 
SelectPF1874 
SelectPF1875 
SelectPF1880 
SelectPF1881 
SelectPF1882 
SelectPF1883 
SelectPF1886 
SelectPF1893 
SelectPF1894 
SelectPF1895 
SelectPF1899 
SelectPF19011
SelectPF1902 
SelectPF19042
SelectPF190932
SelectPF19107
SelectPF191110
SelectPF19124
SelectPF1913 
SelectPF1916 
SelectPF1917 
SelectPF19194
SelectPF1920 
SelectPF1921 
SelectPF1922 
SelectPF1925 
SelectPF1926 
SelectPF19286
SelectPF1930 
SelectPF1931 
SelectPF1932 
SelectPF193315
SelectPF19413
SelectPF194212
SelectPF1943 
SelectPF1945 
SelectPF1946 
SelectPF1947 
SelectPF19483
SelectPF1950 
SelectPF1951 
SelectPF195231
SelectPF19537
SelectPF19545
SelectPF1956 
SelectPF1957 
SelectPF19592
SelectPF196128
SelectPF1962 
SelectPF19641
SelectPF1966 
SelectPF197016
SelectPF19712
SelectPF19729
SelectPF19744
SelectPF1975 
SelectPF19769
SelectPF1977 
SelectPF19782
SelectPF1982 
SelectPF1983 
SelectPF1987 
SelectPF1988 
SelectPF1990 
SelectPF1992 
SelectPF1993 
SelectPF1994 
SelectPF1999 
SelectPF2000 
SelectPF2003 
SelectPF2004 
SelectPF200510
SelectPF20065
SelectPF2007 
SelectPF20084
SelectPF2009 
SelectPF2011 
SelectPF2012 
SelectPF20145
SelectPF2017 
SelectPF2018 
SelectPF2019 
SelectPF2020 
SelectPF2021 
SelectPF2028 
SelectPF20331
SelectPF20388
SelectPF2040 
SelectPF2044 
SelectPF2046 
SelectPF2047 
SelectPF2047.1 
SelectPF20489
SelectPF2050 
SelectPF205128
SelectPF2053 
SelectPF20553